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이향규

소속

  • 간호학과

직위

  • 부교수

연구실 위치

  • 간호대학 516호

전화/팩스

  • 02)2228-3302 / 02)2227-8303

학력사항

  • PhD, Albert Einstein College of Medicine, Graduate programs in the Biomedical Sciences, NY, USA (2002) MS, New York University, School of Art and Science, Biology, NY, USA (1996) BSN, 이화여자대학교 간호대학 간호학과 (1989)

교육 및 연구 경력

  • 2014.9 ~ 2016.8 - 연세대학교 간호대학 교학부원장
    2017.8 ~ 현재 - 부교수, 연세대학교 간호대학 임상간호학과
    2010.9 - 현재 연세대학교 생행동연구센터 센터장
    2017 ~ 2018 - Guest Researcher, National Institute of Nursing Research, NIH, USA
    2009.3 ~ 2017.8 연세대학교 간호대학 임상간호과학과 조교수
    2014.9 ~ 2016.8 - 연세대학교 간호대학 교학부원장
    2006-2009 연구교수, 가톨릭의과학연구소
    2003-2006 Postdoctoral Fellow, Stanford University, Program in Epithelial Biology, CA, USA
    2002-2003 Postdoctoral Fellow, Albert Einstein College of Medicine, NY, USA
    <임상경력>
    1991-1997 Staff RN, Mount Sinai Medical Center, NY, USA
    1989-1991 간호사, 이화여자대학교 의대부속 동대문병원

기타 학술 관련 경력

  • 2009-현재 Asian Nursing Research 논문심사위원
    2009-현재 기초간호자연과학회 심사위원
    2013-현재 한국간호과학회 논문심사위원
    2014 ~ 2017 - 한국기초간호과학회 학술이사
    2014 ~ 2017 - 한국간호과학회 학술위원

연구,관심분야

  • 생행동 연구 (Biobehavioral research), 스트레스와 질병 (Molecular mechanism for stress-induced diseases), 분자생물학 (Molecular biology-signal transduction) 유전간호 (Genetic nursing)

강의분야

  • 생명과학의 이해,기초간호과학,
    병태생리학,생행동연구

논문

  • Capsiate inhibits ultraviolet B-induced skin inflammation by inhibiting Src family kinases and epidermal growth factor receptor signaling
    Free Radical Biology and Medicine, 48(9), 1133-1143, 2010
  • Differential expression of prohibitin and regulation of apoptosis in wild-type and COX-2 null mouse embryonic fibroblasts
    Journal of Dermatological Science, 53(2), 157-159, 2009
  • Reciprocal regulation of 12- and 15-lipoxygenases by UV-irradiation in human keratinocytes
    FEBS Letters, 582(21-22), 3249-3253, 2008
  • Sargaquinoic acid and sargachromenol, extracts of Sargassum sagamianum, induce apoptosis in HaCaT cells and mice skin: Its potentiation of UVB-induced apoptosis
    European Journal of Pharmacology, 582(1-3), 1-11, 2008
  • IFN-γ upregulates expression of the mouse complement C1rA gene in keratinocytes via IFN-regulatory factor-1
    Journal of Investigative Dermatology, 127(5), 1187-1196, 2007
  • Insulin-like growth factor-II regulates the 12-lipoxygenase gene expression and promotes cell proliferation in human keratinocytes via the extracellular regulatory kinase and phosphatidylinositol 3-kinase pathways
    International Journal of Biochemistry and Cell Biology, 39(6), 1248-1259, 2007
  • Identification of phosphocaveolin-1 as a novel protein tyrosine phosphatase 1B substrate
    Biochemistry, 45(1), 234-240. 2006
  • Stromal and epithelial caveolin-1 both confer a protective effect against mammary hyperplasia and tumorigenesis: Caveolin-1 antagonizes cyclin D1 function in mammary epithelial cells
    American Journal of Pathology, 169(5), 1784-1801. 2006
  • Drosophila peptidoglycan recognition protein LC (PGRP-LC) acts as a signal-transducing innate immune receptor
    Proceedings of the National Academy of Sciences of the United States of America, 102(4), 1122-1126. 2005
  • Muscle-specific interaction of caveolin isoforms: Differential complex formation between caveolins in fibroblastic vs. muscle cells
    American Journal of Physiology - Cell Physiology, 288(3 57-3), C677-C691. 2005
  • Adipocyte-derived collagen VI affects early mammary tumor progression in vivo, demonstrating a critical interaction in the tumor/stroma microenvironment
    Journal of Clinical Investigation, 115(5), 1163-1176. 2005
  • Type VII collagen is required for ras-driven human epidermal tumorigenesis
    Science, 307(5716), 1773-1776, 2005
  • Genetic Ablation of Caveolin-1 Confers Protection Against Atherosclerosis
    Arteriosclerosis, Thrombosis, and Vascular Biology, 24(1), 98-105. 2004
  • Tyrosine phosphorylation of caveolin-2 at residue 27: Differences in the spatial and temporal behavior of phospho-Cav-2 (pY19 and pY27)
    Biochemistry, 43(43), 13694-13706. 2004
  • Combined loss of INK4a and caveolin-1 synergistically enhances cell proliferation and oncogene-induced tumorigenesis. Role of INK4a/CAV-1 in mammary epithelial cell hyperplasia
    Journal of Biological Chemistry, 279(23), 24745-24756. 2004
  • Caveolin-1 knockout mice show an impaired angiogenic response to exogenous stimuli
    American Journal of Pathology, 162(6), 2059-2068. 2003
  • Caveolin-1 Null (-/-) Mice Show Dramatic Reductions in Life Span
    Biochemistry, 42(51), 15124-15131. 2003
  • Caveolin-1 mutations (P132L and null) and the pathogenesis of breast cancer: Caveolin-1 (P132L) behaves in a dominant-negative manner and caveolin-1 (-/-) null mice show mammary epithelial cell hyperplasia
    American Journal of Pathology, 161(4), 1357-1369. 2002
  • Intracellular retention of glycosylphosphatidyl inositol-linked proteins in caveolin-deficient cells
    Molecular and Cellular Biology, 22(11), 3905-3926. 2002
  • Caveolin-1-deficient mice show accelerated mammary gland development during pregnancy, premature lactation, and hyperactivation of the Jak-2/STAT5a signaling cascade
    Molecular Biology of the Cell, 13(10), 3416-3430. 2002
  • Src-induced phosphorylation of caveolin-2 on tyrosine 19. Phospho-caveolin-2 (Tyr(P)19) is localized near focal adhesions, remains associated with lipid rafts/caveolae, but no longer forms a high molecular mass hetero-oligomer with caveolin-1
    Journal of Biological Chemistry, 277(37), 34556-34567. 2002
  • Palmitoylation of Caveolin-1 at a Single Site (Cys-156) Controls its Coupling to the c-Src Tyrosine Kinase: Targeting of dually acylated molecules (Gpi-linked, transmembrane, or cytoplasmic) to caveolae effectively uncouples c-Src and caveolin-1 (Tyr-14)
    Journal of Biological Chemistry, 276(37), 35150-35158. 2001
  • Prolactin Negatively Regulates Caveolin-1 Gene Expression in the Mammary Gland during Lactation, via a Ras-dependent Mechanism
    Journal of Biological Chemistry, 276(51), 48389-48397. 2001
  • Tyrosine phosphorylation of beta-dystroglycan at its WW domain binding motif, PPxY, recruits SH2 domain containing proteins
    Biochemistry, 40(48):14585-92. 2001
  • Constitutive and growth factor-regulated phosphorylation of caveolin-1 occurs at the same site (Tyr-14) in vivo: identification of a c-Src/Cav-1/Grb7 signaling cassette
    Molecular Endocrinology. 14(11):1750-75. 2000
  • The lipopolysaccharide-activated toll-like receptor (TLR)-4 induces synthesis of the closely related receptor TLR-2 in adipocytes
    Journal of Biological Chemistry. 275(32):24255-63. 2000
  • Effectiveness of a brief stressmanagement intervention in male college students
    PERSPECTIVES IN PSYCHIATRIC CARE 54/ :88-94,2018
  • 대장암 검진 행동 촉진을 위한 메시지 전략
    한국콘텐츠학회 논문지 17/12 :357-367,2017
  • Visceral adiposity and expression of clock genes in peripheral blood mononuclear cells: A pilot study
    CHRONOBIOLOGY INTERNATIONAL 34/8 :1057-1066,2017
  • 고지방식이에 의한 말초 생체시계 유전자 발현 변화
    Journal of korean biological nursing science 18/4 :305-317,2016
  • Effects of an Integrated Stress Management Program (ISMP) for Psychologically Distressed Students: A Randomized Controlled Trial
    PERSPECTIVES IN PSYCHIATRIC CARE 52/3 :178-185,2016
  • 내과 환자의 섭취량/배설량 측정법 비교 연구
    임상간호연구 22/1 :20-27,2016
  • Factors affecting trajectory of health-related quality of life in COPD patients
    INTERNATIONAL JOURNAL OF TUBERCULOSIS AND LUNG DISEASE 20/6 :738-746,2016
  • Relationship between non-alcoholic fatty liver disease, metabolic syndrome and insulin resistance in Korean adults: A cross-sectional study
    CLINICA CHIMICA ACTA 458/ :12-17,2016
  • Predictors of symptom experience in Korean patients with cancer undergoing chemotherapy
    EUROPEAN JOURNAL OF ONCOLOGY NURSING 19/6 :644-653,2015
  • 고등학생의 신체활동에 따른 수면의 질 및 심박변이도
    Child Health Nursing Research 21/3 :195-203,2015
  • Chronic HMGCR/HMG-CoA Reductase Inhibitor Treatment Contributes to Dysglycemia by Upregulating Hepatic Gluconeogenesis through Autophagy Induction.
    AUTOPHAGY 11/11 :2089-2101,2015
  • The regulation of glucose-6-phosphatase and phosphoenolpyruvate carboxykinase by autophagy in low-glycolytic hepatocellular carcinoma cells
    BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 463/2015 :440-446,2015
  • Oligonol suppresses lipid accumulation and improves insulin resistance in a palmitate-induced in HepG2 hepatocytes as a cellular steatosis model
    BMC COMPLEMENTARY AND ALTERNATIVE MEDICINE 15/185 :1-13,2015
  • 산모의 모유수유 적응과 모유 내 면역물질에 영향을 미치는심리사회적 요인
    여성건강간호학회지 20/1 :14-28,2014
  • Inhibition of Adipogenesis by Oligonol through Akt-mTOR Inhibition in 3T3-L1 Adipocytes
    EVIDENCE-BASED COMPLEMENTARY AND ALTERNATIVE MEDICINE 2014/Arti :1-11,2014
  • Oxidative Stress for the Stroke : A Review of Mechanisms
    한국생활환경학회지 21/4 :532-539,2014
  • 유방암 환자의 증상경험 영향요인: 불쾌증상이론을 중심으로
    Asian Oncology Nursing 14/1 :7-14,2014
  • Predominance of small dense LDL differentiates metabolically unhealthy from metabolically healthy overweight adults in Korea
    METABOLISM-CLINICAL AND EXPERIMENTAL 63/3 :415-421,2014
  • Discovery of DiPeptidyl Peptidase-4 Gene Variants and the Associations with Efficacy of Vildagliptin in Patients with Type 2 Diabetes - A Pilot Study
    JOURNAL OF DIABETES & METABOLISM S13/006 :1-6,2013
  • Understanding of Antioxidants Mechanism in Clinical Nursing Practice
    한국생활환경학회지 20/6 :796-805,2013
  • Visceral adiposity is associated with SIRT1 expression in peripheral blood mononuclear cells: A pilot study.
    ENDOCRINE JOURNAL 60/11 :1269-1273,2013
  • Cu/Zn Incorporation During Purification of Soluble Human EC-SOD from E. coli Stabilizes Proper Disulfide Bond Formation
    APPLIED BIOCHEMISTRY AND BIOTECHNOLOGY 169/5 :1633-1647,2013
  • 동영상 운동프로그램이 항암 화학요법을 받는 암환자의 피로와 신체기능 및 정서상태에 미치는 효과
    임상간호연구 18/3 :368-380,2012
  • Serum Carcinoembryonic Antigen Is Associated with Abdominal Visceral Fat Accumulation in Female Korean Nonsmokers
    PLOS ONE 7/8 :-,2012
  • Requirement for Pak3 in Rac1-induced organization of actin and myosin during Drosophila larval wound healing
    FEBS LETTERS 586/ :772-777,2012
  • 건강캠프에 참여한 학령기 아동의 생행동적 특성과 비만 위험요인
    Journal of Korean Academy of Child Health Nursing 17/4 :207-214,2011
  • 노화관련 질환에서 mTOR의 억제제의 임상적 적용과 가능성
    임상노인의학회지 12/4 :149-159,2011
  • Regulation of skin inflammation and angiogenesis by EC-SOD via HIF-1α and NF-κB pathways
    FREE RADICAL BIOLOGY AND MEDICINE 51/11 :1985-1995,2011
  • Rho-family small GTPases are required for cell polarization and directional sensing in Drosophila wound healing
    BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 394/ :488-492,2010
  • Nonmuscle myosin II localization is regulated by JNK during Drosophila larval wound healing
    BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 393/4 :656-661,2010
  • Drosophila peptidoglycan recognition protein LC (PGRP-LC) acts as a signal-transducing innate immune receptor
    PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 102/4 :1122-1126,2005

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